Thomasville is a North Carolina Main Street community, designated by the N.C. Department of Commerce Main Street & Rural Planning Center. Downtown Thomasville is charged with administering the program at the local level and building public-private partnerships to spur economic development that achieves measurable results such as investment, business growth, and job creation.

As a Main Street America™ Affiliate, Thomasville is part of a national network of neighborhoods and communities that share both a commitment to creating high-quality places and to building stronger communities through preservation-based economic development.